Role of C-Reactive Protein in Contributing to Increased Cardiovascular Risk in Metabolic Syndrome

Metabolic syndrome is associated with increased propensity for diabetes and cardiovascular disease. Low-grade inflammation is characteristic of metabolic syndrome. C-reactive protein, the best characterized biomarker of inflammation, is also an independent predictor of future cardiovascular events....

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Detalles Bibliográficos
Autores principales: Devaraj, Sridevi, Valleggi, Simona, Siegel, David, Jialal, Ishwarlal
Formato: Texto
Lenguaje:English
Publicado: Current Science Inc. 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854398/
https://www.ncbi.nlm.nih.gov/pubmed/20425246
http://dx.doi.org/10.1007/s11883-010-0098-3
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author Devaraj, Sridevi
Valleggi, Simona
Siegel, David
Jialal, Ishwarlal
author_facet Devaraj, Sridevi
Valleggi, Simona
Siegel, David
Jialal, Ishwarlal
author_sort Devaraj, Sridevi
collection PubMed
description Metabolic syndrome is associated with increased propensity for diabetes and cardiovascular disease. Low-grade inflammation is characteristic of metabolic syndrome. C-reactive protein, the best characterized biomarker of inflammation, is also an independent predictor of future cardiovascular events. This review outlines the role of high-sensitivity C-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome by inducing endothelial cell dysfunction and activating monocytes.
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spelling pubmed-28543982010-04-21 Role of C-Reactive Protein in Contributing to Increased Cardiovascular Risk in Metabolic Syndrome Devaraj, Sridevi Valleggi, Simona Siegel, David Jialal, Ishwarlal Curr Atheroscler Rep Article Metabolic syndrome is associated with increased propensity for diabetes and cardiovascular disease. Low-grade inflammation is characteristic of metabolic syndrome. C-reactive protein, the best characterized biomarker of inflammation, is also an independent predictor of future cardiovascular events. This review outlines the role of high-sensitivity C-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome by inducing endothelial cell dysfunction and activating monocytes. Current Science Inc. 2010-03-09 2010 /pmc/articles/PMC2854398/ /pubmed/20425246 http://dx.doi.org/10.1007/s11883-010-0098-3 Text en © The Author(s) 2010 Open AccessThis is an open access article distributed under the terms of the Creative Commons Attribution Noncommercial License (https://creativecommons.org/licenses/by-nc/2.0), which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Article
Devaraj, Sridevi
Valleggi, Simona
Siegel, David
Jialal, Ishwarlal
Role of C-Reactive Protein in Contributing to Increased Cardiovascular Risk in Metabolic Syndrome
title Role of C-Reactive Protein in Contributing to Increased Cardiovascular Risk in Metabolic Syndrome
title_full Role of C-Reactive Protein in Contributing to Increased Cardiovascular Risk in Metabolic Syndrome
title_fullStr Role of C-Reactive Protein in Contributing to Increased Cardiovascular Risk in Metabolic Syndrome
title_full_unstemmed Role of C-Reactive Protein in Contributing to Increased Cardiovascular Risk in Metabolic Syndrome
title_short Role of C-Reactive Protein in Contributing to Increased Cardiovascular Risk in Metabolic Syndrome
title_sort role of c-reactive protein in contributing to increased cardiovascular risk in metabolic syndrome
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854398/
https://www.ncbi.nlm.nih.gov/pubmed/20425246
http://dx.doi.org/10.1007/s11883-010-0098-3
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AT siegeldavid roleofcreactiveproteinincontributingtoincreasedcardiovascularriskinmetabolicsyndrome
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