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Structural basis of wedging the Golgi membrane by FAPP pleckstrin homology domains

The mechanisms underlying Golgi targeting and vesiculation are unknown, although the responsible phosphatidylinositol 4-phosphate (PtdIns(4)P) ligand and four-phosphate-adaptor protein (FAPP) modules have been defined. The micelle-bound structure of the FAPP1 pleckstrin homology domain reveals how i...

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Detalles Bibliográficos
Autores principales:	Lenoir, Marc, Coskun, Ünal, Grzybek, Michal, Cao, Xinwang, Buschhorn, Sabine B, James, Jonathan, Simons, Kai, Overduin, Michael
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Scientific Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854595/ https://www.ncbi.nlm.nih.gov/pubmed/20300118 http://dx.doi.org/10.1038/embor.2010.28

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