MicroRNA Let-7a Inhibits Proliferation of Human Prostate Cancer Cells In Vitro and In Vivo by Targeting E2F2 and CCND2

BACKGROUND: Previous work has shown reduced expression levels of let-7 in lung tumors. But little is known about the expression or mechanisms of let-7a in prostate cancer. In this study, we used in vitro and in vivo approaches to investigate whether E2F2 and CCND2 are direct targets of let-7a, and i...

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Detalles Bibliográficos
Autores principales: Dong, Qingchuan, Meng, Ping, Wang, Tao, Qin, Weiwei, Qin, Weijun, Wang, Fuli, Yuan, Jianlin, Chen, Zhinan, Yang, Angang, Wang, He
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854685/
https://www.ncbi.nlm.nih.gov/pubmed/20418948
http://dx.doi.org/10.1371/journal.pone.0010147

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