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Bromination Pattern of Hydroxylated Metabolites of BDE-47 Affects Their Potency to Release Calcium from Intracellular Stores in PC12 Cells
BACKGROUND: Brominated flame retardants, including the widely used polybrominated diphenyl ethers (PBDEs), have been detected in humans, raising concern about possible neurotoxicity. Recent research demonstrated that the hydroxylated metabolite 6-OH-BDE-47 increases neurotransmitter release by relea...
Autores principales: | Dingemans, Milou M.L., Heusinkveld, Harm J., Bergman, Åke, van den Berg, Martin, Westerink, Remco H.S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
National Institute of Environmental Health Sciences
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2854729/ https://www.ncbi.nlm.nih.gov/pubmed/20368133 http://dx.doi.org/10.1289/ehp.0901339 |
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