Sickle Cell Disease in the Post Genomic Era: A Monogenic Disease with a Polygenic Phenotype

More than half a century after the discovery of the molecular basis of Sickle Cell Disease (SCD), the causes of the phenotypic heterogeneity of the disease remain unclear. This heterogeneity manifests with different clinical outcomes such as stroke, vaso-occlusive episodes, acute chest syndrome, ava...

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Detalles Bibliográficos
Autores principales: Driss, A, Asare, KO, Hibbert, JM, Gee, BE, Adamkiewicz, TV, Stiles, JK
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855197/
https://www.ncbi.nlm.nih.gov/pubmed/20401335

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