Genetic Analysis of Fin Development in Zebrafish Identifies Furin and Hemicentin1 as Potential Novel Fraser Syndrome Disease Genes

Using forward genetics, we have identified the genes mutated in two classes of zebrafish fin mutants. The mutants of the first class are characterized by defects in embryonic fin morphogenesis, which are due to mutations in a Laminin subunit or an Integrin alpha receptor, respectively. The mutants o...

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Detalles Bibliográficos
Autores principales: Carney, Thomas J., Feitosa, Natália Martins, Sonntag, Carmen, Slanchev, Krasimir, Kluger, Johannes, Kiyozumi, Daiji, Gebauer, Jan M., Coffin Talbot, Jared, Kimmel, Charles B., Sekiguchi, Kiyotoshi, Wagener, Raimund, Schwarz, Heinz, Ingham, Phillip W., Hammerschmidt, Matthias
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855323/
https://www.ncbi.nlm.nih.gov/pubmed/20419147
http://dx.doi.org/10.1371/journal.pgen.1000907

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