Cargando…

OptForce: An Optimization Procedure for Identifying All Genetic Manipulations Leading to Targeted Overproductions

Computational procedures for predicting metabolic interventions leading to the overproduction of biochemicals in microbial strains are widely in use. However, these methods rely on surrogate biological objectives (e.g., maximize growth rate or minimize metabolic adjustments) and do not make use of f...

Descripción completa

Detalles Bibliográficos
Autores principales: Ranganathan, Sridhar, Suthers, Patrick F., Maranas, Costas D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855329/
https://www.ncbi.nlm.nih.gov/pubmed/20419153
http://dx.doi.org/10.1371/journal.pcbi.1000744

Ejemplares similares