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Oral Activated Charcoal Prevents Experimental Cerebral Malaria in Mice and in a Randomized Controlled Clinical Trial in Man Did Not Interfere with the Pharmacokinetics of Parenteral Artesunate
BACKGROUND: Safe, cheap and effective adjunct therapies preventing the development of, or reducing the mortality from, severe malaria could have considerable and rapid public health impact. Oral activated charcoal (oAC) is a safe and well tolerated treatment for acute poisoning, more recently shown...
Autores principales: | de Souza, J. Brian, Okomo, Uduak, Alexander, Neal D., Aziz, Naveed, Owens, Benjamin M. J., Kaur, Harparkash, Jasseh, Momodou, Muangnoicharoen, Sant, Sumariwalla, Percy F., Warhurst, David C., Ward, Stephen A., Conway, David J., Ulloa, Luis, Tracey, Kevin J., Foxwell, Brian M. J., Kaye, Paul M., Walther, Michael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855344/ https://www.ncbi.nlm.nih.gov/pubmed/20419161 http://dx.doi.org/10.1371/journal.pone.0009867 |
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