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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

Therapeutics that are designed to engage RNA interference (RNAi) pathways have the potential to provide new, major ways of imparting therapy to patients.1,2 Fire et al. first demonstrated that long, double stranded RNAs mediate RNAi in Caenorhabditis elegans,3 and Elbashir et al. opened the pathway...

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Detalles Bibliográficos
Autores principales:	Davis, Mark E., Zuckerman, Jonathan E., Choi, Chung Hang J., Seligson, David, Tolcher, Anthony, Alabi, Christopher A., Yen, Yun, Heidel, Jeremy D., Ribas, Antoni
Formato:	Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855406/ https://www.ncbi.nlm.nih.gov/pubmed/20305636 http://dx.doi.org/10.1038/nature08956

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