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Efficacy of Limbal-conjunctival Autograft Surgery with Stem Cells in Pterygium Treatment

PURPOSE: To determine the efficacy of limbal-conjunctival autograft surgery with stem cells in the management of primary and recurrent pterygium and determine the best corrected visual acuity after surgery. MATERIALS AND METHODS: Surgical excision of pterygium and limbal-conjunctival transplantation...

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Autor principal: Abdalla, Walid M
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855668/
https://www.ncbi.nlm.nih.gov/pubmed/20404994
http://dx.doi.org/10.4103/0974-9233.58417
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author Abdalla, Walid M
author_facet Abdalla, Walid M
author_sort Abdalla, Walid M
collection PubMed
description PURPOSE: To determine the efficacy of limbal-conjunctival autograft surgery with stem cells in the management of primary and recurrent pterygium and determine the best corrected visual acuity after surgery. MATERIALS AND METHODS: Surgical excision of pterygium and limbal-conjunctival transplantation with stem cells was of 40 eyes (of 31 patients) with pterygium. Thirty one cases were primary and nine cases were recurrent pterygia. Graft margins were secured to the recipient site while stem cells aspect was sutured to the limbus. RESULTS: After one year of follow-up, 37 of 40 (92.5%) eyes were free of recurrence. One of the three recurrent cases was aggressive (recurrence occurred two months after surgery) and the other two showed 2 mm corneal extension at 12 months follow-up. In 24 patients, out of 40 (60%), best corrected visual acuity improved more than two lines. CONCLUSION: Limbal-conjunctival autograft surgery, including stem cells, appears to be an effective surgical technique in preventing pterygium recurrence and it can also help in improving the best corrected visual acuity.
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spelling pubmed-28556682010-04-19 Efficacy of Limbal-conjunctival Autograft Surgery with Stem Cells in Pterygium Treatment Abdalla, Walid M Middle East Afr J Ophthalmol Original Article PURPOSE: To determine the efficacy of limbal-conjunctival autograft surgery with stem cells in the management of primary and recurrent pterygium and determine the best corrected visual acuity after surgery. MATERIALS AND METHODS: Surgical excision of pterygium and limbal-conjunctival transplantation with stem cells was of 40 eyes (of 31 patients) with pterygium. Thirty one cases were primary and nine cases were recurrent pterygia. Graft margins were secured to the recipient site while stem cells aspect was sutured to the limbus. RESULTS: After one year of follow-up, 37 of 40 (92.5%) eyes were free of recurrence. One of the three recurrent cases was aggressive (recurrence occurred two months after surgery) and the other two showed 2 mm corneal extension at 12 months follow-up. In 24 patients, out of 40 (60%), best corrected visual acuity improved more than two lines. CONCLUSION: Limbal-conjunctival autograft surgery, including stem cells, appears to be an effective surgical technique in preventing pterygium recurrence and it can also help in improving the best corrected visual acuity. Medknow Publications 2009 /pmc/articles/PMC2855668/ /pubmed/20404994 http://dx.doi.org/10.4103/0974-9233.58417 Text en © Middle East African Journal of Ophthalmology http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Abdalla, Walid M
Efficacy of Limbal-conjunctival Autograft Surgery with Stem Cells in Pterygium Treatment
title Efficacy of Limbal-conjunctival Autograft Surgery with Stem Cells in Pterygium Treatment
title_full Efficacy of Limbal-conjunctival Autograft Surgery with Stem Cells in Pterygium Treatment
title_fullStr Efficacy of Limbal-conjunctival Autograft Surgery with Stem Cells in Pterygium Treatment
title_full_unstemmed Efficacy of Limbal-conjunctival Autograft Surgery with Stem Cells in Pterygium Treatment
title_short Efficacy of Limbal-conjunctival Autograft Surgery with Stem Cells in Pterygium Treatment
title_sort efficacy of limbal-conjunctival autograft surgery with stem cells in pterygium treatment
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855668/
https://www.ncbi.nlm.nih.gov/pubmed/20404994
http://dx.doi.org/10.4103/0974-9233.58417
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