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Epigenetic Mechanisms Regulate MHC and Antigen Processing Molecules in Human Embryonic and Induced Pluripotent Stem Cells

BACKGROUND: Human embryonic stem cells (hESCs) are an attractive resource for new therapeutic approaches that involve tissue regeneration. hESCs have exhibited low immunogenicity due to low levels of Mayor Histocompatibility Complex (MHC) class-I and absence of MHC class-II expression. Nevertheless,...

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Detalles Bibliográficos
Autores principales: Suárez-Álvarez, Beatriz, Rodriguez, Ramón M., Calvanese, Vincenzo, Blanco-Gelaz, Miguel A., Suhr, Steve T., Ortega, Francisco, Otero, Jesus, Cibelli, Jose B., Moore, Harry, Fraga, Mario F., López-Larrea, Carlos
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855718/
https://www.ncbi.nlm.nih.gov/pubmed/20419139
http://dx.doi.org/10.1371/journal.pone.0010192