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Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery
BACKGROUND: Despite earlier studies demonstrating in vitro propagation of solid tumour cancer stem cells (CSCs) as non-adherent tumour spheres, it remains controversial as to whether CSCs can be maintained in vitro. Additional validation of the CSC properties of tumour spheres would support their us...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855999/ https://www.ncbi.nlm.nih.gov/pubmed/20332776 http://dx.doi.org/10.1038/sj.bjc.6605610 |