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Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery

BACKGROUND: Despite earlier studies demonstrating in vitro propagation of solid tumour cancer stem cells (CSCs) as non-adherent tumour spheres, it remains controversial as to whether CSCs can be maintained in vitro. Additional validation of the CSC properties of tumour spheres would support their us...

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Detalles Bibliográficos
Autores principales:	Fang, D D, Kim, Y J, Lee, C N, Aggarwal, S, McKinnon, K, Mesmer, D, Norton, J, Birse, C E, He, T, Ruben, S M, Moore, P A
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855999/ https://www.ncbi.nlm.nih.gov/pubmed/20332776 http://dx.doi.org/10.1038/sj.bjc.6605610

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