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Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3β phosphorylation

Platelet-derived growth factor CC (PDGF-CC) is the third member of the PDGF family discovered after more than two decades of studies on the original members of the family, PDGF-AA and PDGF-BB. The biological function of PDGF-CC remains largely to be explored. We report a novel finding that PDGF-CC i...

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Detalles Bibliográficos
Autores principales: Tang, Zhongshu, Arjunan, Pachiappan, Lee, Chunsik, Li, Yang, Kumar, Anil, Hou, Xu, Wang, Bin, Wardega, Piotr, Zhang, Fan, Dong, Lijin, Zhang, Yongqing, Zhang, Shi-Zhuang, Ding, Hao, Fariss, Robert N., Becker, Kevin G., Lennartsson, Johan, Nagai, Nobuo, Cao, Yihai, Li, Xuri
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856029/
https://www.ncbi.nlm.nih.gov/pubmed/20231377
http://dx.doi.org/10.1084/jem.20091704