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Antagonism of the complement component C4 by flavivirus nonstructural protein NS1
The complement system plays an essential protective role in the initial defense against many microorganisms. Flavivirus NS1 is a secreted nonstructural glycoprotein that accumulates in blood, is displayed on the surface of infected cells, and has been hypothesized to have immune evasion functions. H...
Autores principales: | Avirutnan, Panisadee, Fuchs, Anja, Hauhart, Richard E., Somnuke, Pawit, Youn, Soonjeon, Diamond, Michael S., Atkinson, John P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856034/ https://www.ncbi.nlm.nih.gov/pubmed/20308361 http://dx.doi.org/10.1084/jem.20092545 |
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