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Targeting iron homeostasis induces cellular differentiation and synergizes with differentiating agents in acute myeloid leukemia

Differentiating agents have been proposed to overcome the impaired cellular differentiation in acute myeloid leukemia (AML). However, only the combinations of all-trans retinoic acid or arsenic trioxide with chemotherapy have been successful, and only in treating acute promyelocytic leukemia (also c...

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Detalles Bibliográficos
Autores principales:	Callens, Celine, Coulon, Séverine, Naudin, Jerome, Radford-Weiss, Isabelle, Boissel, Nicolas, Raffoux, Emmanuel, Wang, Pamella Huey Mei, Agarwal, Saurabh, Tamouza, Houda, Paubelle, Etienne, Asnafi, Vahid, Ribeil, Jean-Antoine, Dessen, Philippe, Canioni, Danielle, Chandesris, Olivia, Rubio, Marie Therese, Beaumont, Carole, Benhamou, Marc, Dombret, Hervé, Macintyre, Elizabeth, Monteiro, Renato C., Moura, Ivan C., Hermine, Olivier
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856037/ https://www.ncbi.nlm.nih.gov/pubmed/20368581 http://dx.doi.org/10.1084/jem.20091488

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