Intra-Tumoral Delivery of shRNA Targeting Cyclin D1 Attenuates Pancreatic Cancer Growth

The aim of this to study was to assess the biological consequences of cyclin D1 silencing in pancreatic cancer cells. A replication-defective lentivirus based small hairpin RNA (shRNA) system targeting cyclin D1 caused a marked reduction in cyclin D1 protein levels in ASPC-1 and BxPC3 pancreatic can...

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Detalles Bibliográficos
Autores principales: Deharvengt, Sophie J., Gunn, Jason R., Pickett, Sarah B., Korc, Murray
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856737/
https://www.ncbi.nlm.nih.gov/pubmed/19851352
http://dx.doi.org/10.1038/cgt.2009.75

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856737/
https://www.ncbi.nlm.nih.gov/pubmed/19851352
http://dx.doi.org/10.1038/cgt.2009.75

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