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Intra-Tumoral Delivery of shRNA Targeting Cyclin D1 Attenuates Pancreatic Cancer Growth
The aim of this to study was to assess the biological consequences of cyclin D1 silencing in pancreatic cancer cells. A replication-defective lentivirus based small hairpin RNA (shRNA) system targeting cyclin D1 caused a marked reduction in cyclin D1 protein levels in ASPC-1 and BxPC3 pancreatic can...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856737/ https://www.ncbi.nlm.nih.gov/pubmed/19851352 http://dx.doi.org/10.1038/cgt.2009.75 |