Cargando…
HPat provides a link between deadenylation and decapping in metazoa
Decapping of eukaryotic messenger RNAs (mRNAs) occurs after they have undergone deadenylation, but how these processes are coordinated is poorly understood. In this study, we report that Drosophila melanogaster HPat (homologue of Pat1), a conserved decapping activator, interacts with additional deca...
Autores principales: | Haas, Gabrielle, Braun, Joerg E., Igreja, Cátia, Tritschler, Felix, Nishihara, Tadashi, Izaurralde, Elisa |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856893/ https://www.ncbi.nlm.nih.gov/pubmed/20404111 http://dx.doi.org/10.1083/jcb.200910141 |
Ejemplares similares
-
The C-terminal α–α superhelix of Pat is required for mRNA decapping in metazoa
por: Braun, Joerg E, et al.
Publicado: (2010) -
4E-T-bound mRNAs are stored in a silenced and deadenylated form
por: Räsch, Felix, et al.
Publicado: (2020) -
A low-complexity region in human XRN1 directly recruits deadenylation and decapping factors in 5′–3′ messenger RNA decay
por: Chang, Chung-Te, et al.
Publicado: (2019) -
miRISC recruits decapping factors to miRNA targets to enhance their degradation
por: Nishihara, Tadashi, et al.
Publicado: (2013) -
HPat a Decapping Activator Interacting with the miRNA Effector Complex
por: Barišić-Jäger, Elisabeth, et al.
Publicado: (2013)