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Activation of cyclin B1–Cdk1 synchronizes events in the nucleus and the cytoplasm at mitosis
The cyclin B–Cdk1 kinase triggers mitosis in most eukaryotes. In animal cells, cyclin B shuttles between the nucleus and cytoplasm in interphase before rapidly accumulating in the nucleus at prophase, which promotes disassembly of the nuclear lamina and nuclear envelope breakdown (NEBD). What trigge...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856909/ https://www.ncbi.nlm.nih.gov/pubmed/20404109 http://dx.doi.org/10.1083/jcb.200909144 |