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αvβ3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration

Integrins are fundamental to the control of protrusion and motility in adherent cells. However, the mechanisms by which specific members of this receptor family cooperate in signaling to cytoskeletal and adhesion dynamics are poorly understood. Here, we show that the loss of β3 integrin in fibroblas...

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Detalles Bibliográficos
Autores principales: Worth, Daniel C., Hodivala-Dilke, Kairbaan, Robinson, Stephen D., King, Samantha J., Morton, Penny E., Gertler, Frank B., Humphries, Martin J., Parsons, Maddy
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856911/
https://www.ncbi.nlm.nih.gov/pubmed/20404115
http://dx.doi.org/10.1083/jcb.200912014