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Dynamic Regulation of a Metabolic Multi-enzyme Complex by Protein Kinase CK2

The reversible association and dissociation of a metabolic multi-enzyme complex participating in de novo purine biosynthesis, the purinosome, was demonstrated in live cells to respond to the levels of purine nucleotides in the culture media. We also took advantage of in vitro proteomic scale studies...

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Detalles Bibliográficos
Autores principales:	An, Songon, Kyoung, Minjoung, Allen, Jasmina J., Shokat, Kevan M., Benkovic, Stephen J.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2010
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856985/ https://www.ncbi.nlm.nih.gov/pubmed/20157113 http://dx.doi.org/10.1074/jbc.M110.101139

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