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The NPH-II Helicase Displays Efficient DNA·RNA Helicase Activity and a Pronounced Purine Sequence Bias

The superfamily 2 vaccinia viral helicase nucleoside triphosphate phosphohydrolase-II (NPH-II) exhibits robust RNA helicase activity but typically displays little activity on DNA substrates. NPH-II is thus believed to make primary contacts with backbone residues of an RNA substrate. We report an unu...

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Detalles Bibliográficos
Autores principales:	Taylor, Sean David, Solem, Amanda, Kawaoka, Jane, Pyle, Anna Marie
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2010
Materias:	Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857044/ https://www.ncbi.nlm.nih.gov/pubmed/20110368 http://dx.doi.org/10.1074/jbc.M109.088559

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