Reduced Sensitivity of Influenza A (H5N1) to Oseltamivir

We tested the neuraminidase drug sensitivity of clade 1 and clade 2 influenza A virus (H5N1). All viruses demonstrated similar sensitivity to zanamivir, but compared to the 2004 clade 1 viruses, the Cambodian 2005 viruses were 6-fold less sensitive and the Indonesian clade 2 viruses were up to 30-fo...

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Autores principales: McKimm-Breschkin, Jennifer L., Selleck, Paul W., Usman, Tri Bhakti, Johnson, Michael A.
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2007
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857286/
https://www.ncbi.nlm.nih.gov/pubmed/18252107
http://dx.doi.org/10.3201/eid1309.07-0164
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author McKimm-Breschkin, Jennifer L.
Selleck, Paul W.
Usman, Tri Bhakti
Johnson, Michael A.
author_facet McKimm-Breschkin, Jennifer L.
Selleck, Paul W.
Usman, Tri Bhakti
Johnson, Michael A.
author_sort McKimm-Breschkin, Jennifer L.
collection PubMed
description We tested the neuraminidase drug sensitivity of clade 1 and clade 2 influenza A virus (H5N1). All viruses demonstrated similar sensitivity to zanamivir, but compared to the 2004 clade 1 viruses, the Cambodian 2005 viruses were 6-fold less sensitive and the Indonesian clade 2 viruses were up to 30-fold less sensitive to oseltamivir.
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spelling pubmed-28572862010-05-06 Reduced Sensitivity of Influenza A (H5N1) to Oseltamivir McKimm-Breschkin, Jennifer L. Selleck, Paul W. Usman, Tri Bhakti Johnson, Michael A. Emerg Infect Dis Dispatch We tested the neuraminidase drug sensitivity of clade 1 and clade 2 influenza A virus (H5N1). All viruses demonstrated similar sensitivity to zanamivir, but compared to the 2004 clade 1 viruses, the Cambodian 2005 viruses were 6-fold less sensitive and the Indonesian clade 2 viruses were up to 30-fold less sensitive to oseltamivir. Centers for Disease Control and Prevention 2007-09 /pmc/articles/PMC2857286/ /pubmed/18252107 http://dx.doi.org/10.3201/eid1309.07-0164 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
McKimm-Breschkin, Jennifer L.
Selleck, Paul W.
Usman, Tri Bhakti
Johnson, Michael A.
Reduced Sensitivity of Influenza A (H5N1) to Oseltamivir
title Reduced Sensitivity of Influenza A (H5N1) to Oseltamivir
title_full Reduced Sensitivity of Influenza A (H5N1) to Oseltamivir
title_fullStr Reduced Sensitivity of Influenza A (H5N1) to Oseltamivir
title_full_unstemmed Reduced Sensitivity of Influenza A (H5N1) to Oseltamivir
title_short Reduced Sensitivity of Influenza A (H5N1) to Oseltamivir
title_sort reduced sensitivity of influenza a (h5n1) to oseltamivir
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857286/
https://www.ncbi.nlm.nih.gov/pubmed/18252107
http://dx.doi.org/10.3201/eid1309.07-0164
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