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Polarised fluid movement, and not cell death creates luminal spaces in adult prostate epithelium
There are two predominant theories for lumen formation in tissue morphogenesis; cavitation driven by cell death, and membrane separation driven by epithelial polarity. To define the mechanism of lumen formation in prostate acini we examined both theories in several cell lines grown in 3D Matrigel cu...
Autores principales: | Pearson, Joanna Frances, Hughes, Siobhan, Chambers, Karen, Lang, Shona Helen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857323/ https://www.ncbi.nlm.nih.gov/pubmed/19096393 http://dx.doi.org/10.1038/cdd.2008.181 |
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