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TGF-β induces apoptosis in human B cells via transcriptional regulation of BIK and BCL-X(L)

TGF-β potently induces apoptosis in Burkitt’s Lymphoma (BL) cell lines and in explanted primary human B lymphocytes. The physiological relevance and mechanism of TGF-β-mediated apoptosis induction in these cells remains to be determined. Here we demonstrate the requirement for TGF-β-mediated regulat...

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Detalles Bibliográficos
Autores principales:	Spender, LC, O’Brien, DI, Simpson, D, Dutt, D, Gregory, CD, Allday, MJ, Clark, LJ, Inman, GJ
Formato:	Texto
Lenguaje:	English
Publicado:	2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857326/ https://www.ncbi.nlm.nih.gov/pubmed/19136942 http://dx.doi.org/10.1038/cdd.2008.183

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