Malignant Precursor Cells Pre-Exist in Human Breast DCIS and Require Autophagy for Survival

BACKGROUND: While it is accepted that a majority of invasive breast cancer progresses from a ductal carcinoma in situ (DCIS) precursor stage, very little is known about the factors that promote survival of DCIS neoplastic cells within the hypoxic, nutrient deprived intraductal microenvironment. METH...

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Detalles Bibliográficos
Autores principales: Espina, Virginia, Mariani, Brian D., Gallagher, Rosa I., Tran, Khoa, Banks, Stacey, Wiedemann, Joy, Huryk, Heather, Mueller, Claudius, Adamo, Luana, Deng, Jianghong, Petricoin, Emanuel F., Pastore, Lucia, Zaman, Syed, Menezes, Geetha, Mize, James, Johal, Jasbir, Edmiston, Kirsten, Liotta, Lance A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857649/
https://www.ncbi.nlm.nih.gov/pubmed/20421921
http://dx.doi.org/10.1371/journal.pone.0010240

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