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A Single Amino Acid Change Converts the Sugar Sensor SGLT3 into a Sugar Transporter
BACKGROUND: Sodium-glucose cotransporter proteins (SGLT) belong to the SLC5A family, characterized by the cotransport of Na(+) with solute. SGLT1 is responsible for intestinal glucose absorption. Until recently the only role described for SGLT proteins was to transport sugar with Na(+). However, hum...
Autores principales: | Bianchi, Laura, Díez-Sampedro, Ana |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857651/ https://www.ncbi.nlm.nih.gov/pubmed/20421923 http://dx.doi.org/10.1371/journal.pone.0010241 |
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