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Influence of production process design on inclusion bodies protein: the case of an Antarctic flavohemoglobin
BACKGROUND: Protein over-production in Escherichia coli often results in formation of inclusion bodies (IBs). Some recent reports have shown that the aggregation into IBs does not necessarily mean that the target protein is inactivated and that IBs may contain a high proportion of correctly folded p...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857821/ https://www.ncbi.nlm.nih.gov/pubmed/20334669 http://dx.doi.org/10.1186/1475-2859-9-19 |