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Linking toxicant physiological mode of action with induced gene expression changes in Caenorhabditis elegans
BACKGROUND: Physiologically based modelling using DEBtox (dynamic energy budget in toxicology) and transcriptional profiling were used in Caenorhabditis elegans to identify how physiological modes of action, as indicated by effects on system level resource allocation were associated with changes in...
Autores principales: | Swain, Suresh, Wren, Jodie F, Stürzenbaum, Stephen R, Kille, Peter, Morgan, A John, Jager, Tjalling, Jonker, Martijs J, Hankard, Peter K, Svendsen, Claus, Owen, Jenifer, Hedley, B Ann, Blaxter, Mark, Spurgeon, David J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857823/ https://www.ncbi.nlm.nih.gov/pubmed/20331876 http://dx.doi.org/10.1186/1752-0509-4-32 |
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