Silencing of the JNK pathway maintains progesterone receptor activity in decidualizing human endometrial stromal cells exposed to oxidative stress signals

Survival of the conceptus is dependent on continuous progesterone signaling in the maternal decidua but how this is achieved under conditions of oxidative stress that characterize early pregnancy is unknown. Using primary cultures, we show that modest levels of reactive oxygen species (ROS) increase...

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Detalles Bibliográficos
Autores principales: Leitao, Beatriz, Jones, Marius C., Fusi, Luca, Higham, Jenny, Lee, Yun, Takano, Masashi, Goto, Tomoko, Christian, Mark, Lam, Eric W.-F., Brosens, Jan J.
Formato: Texto
Lenguaje:English
Publicado: The Federation of American Societies for Experimental Biology 2010
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857868/
https://www.ncbi.nlm.nih.gov/pubmed/20026682
http://dx.doi.org/10.1096/fj.09-149153

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