Cargando…

Immunoregulatory Actions of Epithelial Cell PPAR γ at the Colonic Mucosa of Mice with Experimental Inflammatory Bowel Disease

BACKGROUND: Peroxisome proliferator-activated receptors are nuclear receptors highly expressed in intestinal epithelial cells (IEC) and immune cells within the gut mucosa and are implicated in modulating inflammation and immune responses. The objective of this study was to investigate the effect of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mohapatra, Saroj K., Guri, Amir J., Climent, Montse, Vives, Cristina, Carbo, Adria, Horne, William T., Hontecillas, Raquel, Bassaganya-Riera, Josep
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857885/ https://www.ncbi.nlm.nih.gov/pubmed/20422041 http://dx.doi.org/10.1371/journal.pone.0010215

Ejemplares similares

Immunoregulatory mechanisms of macrophage PPAR γ in mice with experimental inflammatory bowel disease
por: Hontecillas, Raquel, et al.
Publicado: (2010)

The Role of T cell PPAR γ in mice with experimental inflammatory bowel disease
por: Guri, Amir J, et al.
Publicado: (2010)

Treatment of Obesity-Related Complications with Novel Classes of Naturally Occurring PPAR Agonists
por: Bassaganya-Riera, Josep, et al.
Publicado: (2011)

Helicobacter pylori Colonization Ameliorates Glucose Homeostasis in Mice through a PPAR γ-Dependent Mechanism
por: Bassaganya-Riera, Josep, et al.
Publicado: (2012)

Dietary Modulation of Inflammation-Induced Colorectal Cancer through PPARγ
por: Carter, Ashlee B., et al.
Publicado: (2009)

Dietary α-Eleostearic Acid Ameliorates Experimental Inflammatory Bowel Disease in Mice by Activating Peroxisome Proliferator-Activated Receptor-γ
por: Lewis, Stephanie N., et al.
Publicado: (2011)

Immunoregulatory Mechanisms Underlying Prevention of Colitis-Associated Colorectal Cancer by Probiotic Bacteria
por: Bassaganya-Riera, Josep, et al.
Publicado: (2012)

Probiotic Bacteria Produce Conjugated Linoleic Acid Locally in the Gut That Targets Macrophage PPAR γ to Suppress Colitis
por: Bassaganya-Riera, Josep, et al.
Publicado: (2012)

Computational modeling of heterogeneity and function of CD4+ T cells
por: Carbo, Adria, et al.
Publicado: (2014)

Supervised learning methods in modeling of CD4+ T cell heterogeneity
por: Lu, Pinyi, et al.
Publicado: (2015)

Computational Modeling-Based Discovery of Novel Classes of Anti-Inflammatory Drugs That Target Lanthionine Synthetase C-Like Protein 2
por: Lu, Pinyi, et al.
Publicado: (2012)

Modulation of hepatic PPAR expression during Ft LVS LPS-induced protection from Francisella tularensis LVS infection
por: Mohapatra, Saroj K, et al.
Publicado: (2010)

Phosphorylation of PPARγ Affects the Collective Motions of the PPARγ-RXRα-DNA Complex
por: Lemkul, Justin A., et al.
Publicado: (2015)

Deletion of PPAR-γ in immune cells enhances susceptibility to antiglomerular basement membrane disease
por: Chafin, Cristen, et al.
Publicado: (2010)

Modeling-Enabled Systems Nutritional Immunology
por: Verma, Meghna, et al.
Publicado: (2016)

Modeling the Role of Peroxisome Proliferator-Activated Receptor γ and MicroRNA-146 in Mucosal Immune Responses to Clostridium difficile
por: Viladomiu, Monica, et al.
Publicado: (2012)

Multiscale modeling of mucosal immune responses
por: Mei, Yongguo, et al.
Publicado: (2015)

Modeling the Mechanisms by Which HIV-Associated Immunosuppression Influences HPV Persistence at the Oral Mucosa
por: Verma, Meghna, et al.
Publicado: (2017)

NLRX1 Modulates Immunometabolic Mechanisms Controlling the Host–Gut Microbiota Interactions during Inflammatory Bowel Disease
por: Leber, Andrew, et al.
Publicado: (2018)

Preventive and Prophylactic Mechanisms of Action of Pomegranate Bioactive Constituents
por: Viladomiu, Monica, et al.
Publicado: (2013)

Sensitivity Analysis of an ENteric Immunity SImulator (ENISI)-Based Model of Immune Responses to Helicobacter pylori Infection
por: Alam, Maksudul, et al.
Publicado: (2015)

Abscisic Acid: A Novel Nutraceutical for Glycemic Control
por: Zocchi, Elena, et al.
Publicado: (2017)

The Role of Peroxisome Proliferator-Activated Receptor γ in Immune Responses to Enteroaggregative Escherichia coli Infection
por: Philipson, Casandra W., et al.
Publicado: (2013)

Systems Modeling of the Role of Interleukin-21 in the Maintenance of Effector CD4(+) T Cell Responses during Chronic Helicobacter pylori Infection
por: Carbo, Adria, et al.
Publicado: (2014)

Gene regulatory network reveals oxidative stress as the underlying molecular mechanism of type 2 diabetes and hypertension
por: Jesmin, et al.
Publicado: (2010)

Challenges in Personalized Nutrition and Health
por: Verma, Meghna, et al.
Publicado: (2018)

Virtual Screening as a Technique for PPAR Modulator Discovery
por: Lewis, Stephanie N., et al.
Publicado: (2010)

Predictive Computational Modeling of the Mucosal Immune Responses during Helicobacter pylori Infection
por: Carbo, Adria, et al.
Publicado: (2013)

Modeling-Enabled Characterization of Novel NLRX1 Ligands
por: Lu, Pinyi, et al.
Publicado: (2015)

First-in-class topical therapeutic omilancor ameliorates disease severity and inflammation through activation of LANCL2 pathway in psoriasis
por: Tubau-Juni, Nuria, et al.
Publicado: (2021)

Systems Modeling of Molecular Mechanisms Controlling Cytokine-driven CD4+ T Cell Differentiation and Phenotype Plasticity
por: Carbo, Adria, et al.
Publicado: (2013)

Abscisic acid enriched fig extract promotes insulin sensitivity by decreasing systemic inflammation and activating LANCL2 in skeletal muscle
por: Leber, Andrew, et al.
Publicado: (2020)

Computational modeling of complex bioenergetic mechanisms that modulate CD4+ T cell effector and regulatory functions
por: Baker, Ryan, et al.
Publicado: (2022)

Modulation of colonic immunometabolic responses during Clostridioides difficile infection ameliorates disease severity and inflammation
por: Tubau-Juni, Nuria, et al.
Publicado: (2023)

PPARγ in Inflammatory Bowel Disease
por: Annese, Vito, et al.
Publicado: (2012)

PPARβ/δ-Interfering Peptide Enhanced Mesenchymal Stromal Cell Immunoregulatory Properties
por: Tejedor, Gautier, et al.
Publicado: (2022)

Systems Modeling of Interactions between Mucosal Immunity and the Gut Microbiome during Clostridium difficile Infection
por: Leber, Andrew, et al.
Publicado: (2015)

Nlrx1-Regulated Defense and Metabolic Responses to Aspergillus fumigatus Are Morphotype and Cell Type Specific
por: Kastelberg, Bridget, et al.
Publicado: (2021)

High-resolution computational modeling of immune responses in the gut
por: Verma, Meghna, et al.
Publicado: (2019)

Modeling the Role of Lanthionine Synthetase C-Like 2 (LANCL2) in the Modulation of Immune Responses to Helicobacter pylori Infection
por: Leber, Andrew, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_5ndh12rtubd9s8d63nit054hqm