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Accelerated Increase in Serum Interleukin-1 Receptor Antagonist Starts 6 Years Before Diagnosis of Type 2 Diabetes: Whitehall II Prospective Cohort Study
OBJECTIVE: Although interleukin-1 receptor antagonist (IL-1Ra) treatment is associated with improved β-cell function and glycemic control in patients with type 2 diabetes, its role in the development of type 2 diabetes remains unclear. We used repeated measurements to characterize IL-1Ra trajectorie...
Autores principales: | Carstensen, Maren, Herder, Christian, Kivimäki, Mika, Jokela, Markus, Roden, Michael, Shipley, Martin J., Witte, Daniel R., Brunner, Eric J., Tabák, Adam G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857902/ https://www.ncbi.nlm.nih.gov/pubmed/20185814 http://dx.doi.org/10.2337/db09-1199 |
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