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Relative roles of the different Pax6 domains for pancreatic alpha cell development

BACKGROUND: The transcription factor Pax6 functions in the specification and maintenance of the differentiated cell lineages in the endocrine pancreas. It has two DNA binding domains, the paired domain and the homeodomain, in addition to a C-terminal transactivation domain. The phenotype of Pax6(-/-...

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Detalles Bibliográficos
Autores principales:	Dames, Petra, Puff, Ramona, Weise, Michaela, Parhofer, Klaus G, Göke, Burkhard, Götz, Magdalena, Graw, Jochen, Favor, Jack, Lechner, Andreas
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858030/ https://www.ncbi.nlm.nih.gov/pubmed/20377917 http://dx.doi.org/10.1186/1471-213X-10-39

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