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A Novel Fibroblast Growth Factor-1 (FGF1) Mutant that Acts as an FGF Antagonist

BACKGROUND: Crosstalk between integrins and FGF receptors has been implicated in FGF signaling, but the specifics of the crosstalk are unclear. We recently discovered that 1) FGF1 directly binds to integrin αvβ3, 2) the integrin-binding site and FGF receptor (FGFR) binding site are distinct, and 3)...

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Detalles Bibliográficos
Autores principales:	Yamaji, Satoshi, Saegusa, Jun, Ieguchi, Katsuaki, Fujita, Masaaki, Mori, Seiji, Takada, Yoko K., Takada, Yoshikazu
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858075/ https://www.ncbi.nlm.nih.gov/pubmed/20422052 http://dx.doi.org/10.1371/journal.pone.0010273

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