Rapid Progressing Allele HLA-B35 Px Restricted Anti-HIV-1 CD8+ T Cells Recognize Vestigial CTL Epitopes

BACKGROUND: The HLA-B*35-Px allele has been associated with rapid disease progression in HIV-1 infection, in contrast to the HLA-B*35-Py allele. METHODOLOGY/PRINCIPAL FINDINGS: Immune responses to two HLA-B*35 restricted HIV-1 specific CTL epitopes and their variants were followed longitudinally dur...

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Detalles Bibliográficos
Autores principales: Willberg, Christian B., Garrison, Keith E., Jones, R. Brad, Meiklejohn, Duncan J., Spotts, Gerald, Liegler, Teri J., Ostrowski, Mario A., Karlsson, Annika C., Hecht, Frederick M., Nixon, Douglas F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858076/
https://www.ncbi.nlm.nih.gov/pubmed/20422053
http://dx.doi.org/10.1371/journal.pone.0010249

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