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Genetic and epigenetic silencing of the beclin 1 gene in sporadic breast tumors
BACKGROUND: Beclin 1, an important autophagy-related protein in human cells, is involved in cell death and cell survival. Beclin 1 mapped to human chromosome 17q21. It is widely expressed in normal mammary epithelial cells. Although down-regulated expression with mono-allelic deletions of beclin 1 g...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858113/ https://www.ncbi.nlm.nih.gov/pubmed/20230646 http://dx.doi.org/10.1186/1471-2407-10-98 |