Cargando…

Maternal inheritance and mitochondrial DNA variants in familial Parkinson's disease

BACKGROUND: Mitochondrial function is impaired in Parkinson's disease (PD) and may contribute to the pathogenesis of PD, but the causes of mitochondrial impairment in PD are unknown. Mitochondrial dysfunction is recapitulated in cell lines expressing mitochondrial DNA (mtDNA) from PD patients,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Simon, David K, Pankratz, Nathan, Kissell, Diane K, Pauciulo, Michael W, Halter, Cheryl A, Rudolph, Alice, Pfeiffer, Ronald F, Nichols, William C, Foroud, Tatiana
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858137/ https://www.ncbi.nlm.nih.gov/pubmed/20356410 http://dx.doi.org/10.1186/1471-2350-11-53

Ejemplares similares

Genomewide association study for onset age in Parkinson disease
por: Latourelle, Jeanne C, et al.
Publicado: (2009)

Copy Number Variation in Familial Parkinson Disease
por: Pankratz, Nathan, et al.
Publicado: (2011)

Standard linkage and association methods identify the mechanism of four susceptibility genes for a simulated complex disease
por: Pankratz, Nathan, et al.
Publicado: (2005)

Mitochondrial mutations in maternally inherited hearing loss
por: Mutai, Hideki, et al.
Publicado: (2017)

Keeping in Shape the Dogma of Mitochondrial DNA Maternal Inheritance
por: Carelli, Valerio
Publicado: (2015)

Identification of genes for complex disease using longitudinal phenotypes
por: Pankratz, Nathan, et al.
Publicado: (2003)

Mitochondrial genome study in blood of maternally inherited ALS cases
por: Brockmann, Sarah J., et al.
Publicado: (2023)

Oxidative Stress: Mechanistic Insights into Inherited Mitochondrial Disorders and Parkinson’s Disease
por: Al Shahrani, Mesfer, et al.
Publicado: (2017)

Maternal Inheritance of U’s Triangle and Evolutionary Process of Brassica Mitochondrial Genomes
por: Xue, Jia-Yu, et al.
Publicado: (2020)

Paternal leakage of mitochondrial DNA and maternal inheritance of heteroplasmy in Drosophila hybrids
por: Polovina, Eirini-Slavka, et al.
Publicado: (2020)

The mutational analysis of mitochondrial DNA in maternal inheritance of polycystic ovarian syndrome
por: Bibi, Shaheen, et al.
Publicado: (2023)

Gene Expression Profiles in Parkinson Disease Prefrontal Cortex Implicate FOXO1 and Genes under Its Transcriptional Regulation
por: Dumitriu, Alexandra, et al.
Publicado: (2012)

Maternal patterns of inheritance alter transcript expression in eggs
por: Harry, Nathan D., et al.
Publicado: (2023)

Influence of Maternal Aging on Mitochondrial Heterogeneity, Inheritance, and Function in Oocytes and Preimplantation Embryos
por: Woods, Dori C., et al.
Publicado: (2018)

Maternally Inherited Differences within Mitochondrial Complex I Control Murine Healthspan
por: Hirose, Misa, et al.
Publicado: (2019)

A Novel Unstable Mutation in Mitochondrial DNA Responsible for Maternally Inherited Diabetes and Deafness
por: Bannwarth, Sylvie, et al.
Publicado: (2011)

Mitochondrial Deoxyribonucleic Acid (mtDNA), Maternal Inheritance, and Their Role in the Development of Cancers: A Scoping Review
por: Vadakedath, Sabitha, et al.
Publicado: (2023)

The Familial Intracranial Aneurysm (FIA) study protocol
por: Broderick, Joseph P, et al.
Publicado: (2005)

Phenotypic spectrum of maternally inherited Leigh Syndrome associated with the m.8993T>G variant
por: Gropman, Andrea, et al.
Publicado: (2018)

Inherited mitochondrial optic neuropathies
por: Yu-Wai-Man, P, et al.
Publicado: (2009)

Mitochondrial DNA 7908–8816 region mutations in maternally inherited essential hypertensive subjects in China
por: Zhu, Ye, et al.
Publicado: (2018)

Maternally inherited coronary heart disease is associated with a novel mitochondrial tRNA mutation
por: Zhang, Zhenxiao, et al.
Publicado: (2019)

Mitochondrial tRNA Mutation and Regulation of the Adiponectin Pathway in Maternally Inherited Hypertension in Chinese Han
por: Bai, Jing, et al.
Publicado: (2021)

Inherited common variants in mitochondrial DNA and invasive serous epithelial ovarian cancer risk
por: Earp, Madalene A, et al.
Publicado: (2013)

Obscurin variants and inherited cardiomyopathies
por: Marston, Steven
Publicado: (2017)

Noninvasive Fetal Genotyping by Droplet Digital PCR to Identify Maternally Inherited Monogenic Diabetes Variants
por: Caswell, Richard C., et al.
Publicado: (2020)

THU143 A Novel Maternally Inherited GNAS Variant In A Family With Hyperphagia And Obesity
por: Purushothaman, Preetha, et al.
Publicado: (2023)

Novel recruitment strategy to enrich for LRRK2 mutation carriers
por: Foroud, Tatiana, et al.
Publicado: (2015)

Systematic analysis of the clinical and biochemical characteristics of maternally inherited hypertension in Chinese Han families associated with mitochondrial
por: Liu, Yuqi, et al.
Publicado: (2014)

The Complete Maternally and Paternally Inherited Mitochondrial Genomes of a Freshwater Mussel Potamilus alatus (Bivalvia: Unionidae)
por: Wen, Hai B., et al.
Publicado: (2017)

Associations of mitochondrial DNA 3777–4679 region mutations with maternally inherited essential hypertensive subjects in China
por: Zhu, Ye, et al.
Publicado: (2020)

The inheritance of pathogenic mitochondrial DNA mutations
por: Cree, L.M., et al.
Publicado: (2009)

Maternally inherited genetic variants of CADPS2 are present in Autism Spectrum Disorders and Intellectual Disability patients
por: Bonora, Elena, et al.
Publicado: (2014)

Maternally inherited genetic variants of CADPS2 are present in Autism Spectrum Disorders and Intellectual Disability patients
por: Bonora, Elena, et al.
Publicado: (2014)

Whole-exome sequencing in 415,422 individuals identifies rare variants associated with mitochondrial DNA copy number
por: Pillalamarri, Vamsee, et al.
Publicado: (2022)

Commentary: Heteroplasmy in maternally inherited diabetes and deafness
por: Panchal, Bhavik, et al.
Publicado: (2020)

Diabetes predisposition inherited through maternal germline
por: Zhu, Hong, et al.
Publicado: (2022)

Additional rare variant analysis in Parkinson’s disease cases with and without known pathogenic mutations: evidence for oligogenic inheritance
por: Lubbe, Steven J., et al.
Publicado: (2016)

Single-cell epigenomic analyses implicate candidate causal variants at inherited risk loci for Alzheimer’s and Parkinson’s diseases
por: Corces, M. Ryan, et al.
Publicado: (2020)

Expression of Concern: Mitochondrial tRNA mutation and regulation of the adiponectin pathway in maternally inherited hypertension in Chinese Han
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_e7dta51sndd4460gtlmbd9d8uu