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A stress-responsive RNA switch regulates VEGF expression

Ligand binding to structural elements in noncoding regions of mRNA modulates gene expression1,2. Ligands such as free metabolites or other small molecules directly bind and induce conformational changes in regulatory RNA elements known as riboswitches1-4. Other types of RNA switches are activated by...

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Detalles Bibliográficos
Autores principales: Ray, Partho Sarothi, Jia, Jie, Yao, Peng, Majumder, Mithu, Hatzoglou, Maria, Fox, Paul L.
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858559/
https://www.ncbi.nlm.nih.gov/pubmed/19098893
http://dx.doi.org/10.1038/nature07598