FAM-MDR: A Flexible Family-Based Multifactor Dimensionality Reduction Technique to Detect Epistasis Using Related Individuals

We propose a novel multifactor dimensionality reduction method for epistasis detection in small or extended pedigrees, FAM-MDR. It combines features of the Genome-wide Rapid Association using Mixed Model And Regression approach (GRAMMAR) with Model-Based MDR (MB-MDR). We focus on continuous traits,...

Descripción completa

Detalles Bibliográficos
Autores principales: Cattaert, Tom, Urrea, Víctor, Naj, Adam C., De Lobel, Lizzy, De Wit, Vanessa, Fu, Mao, Mahachie John, Jestinah M., Shen, Haiqing, Calle, M. Luz, Ritchie, Marylyn D., Edwards, Todd L., Van Steen, Kristel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858665/
https://www.ncbi.nlm.nih.gov/pubmed/20421984
http://dx.doi.org/10.1371/journal.pone.0010304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858665/
https://www.ncbi.nlm.nih.gov/pubmed/20421984
http://dx.doi.org/10.1371/journal.pone.0010304

Ejemplares similares