Hypomethylation of a LINE-1 Promoter Activates an Alternate Transcript of the MET Oncogene in Bladders with Cancer

It was recently shown that a large portion of the human transcriptome can originate from within repetitive elements, leading to ectopic expression of protein-coding genes. However the mechanism of transcriptional activation of repetitive elements has not been definitively elucidated. For the first t...

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Detalles Bibliográficos
Autores principales: Wolff, Erika M., Byun, Hyang-Min, Han, Han F., Sharma, Shikhar, Nichols, Peter W., Siegmund, Kimberly D., Yang, Allen S., Jones, Peter A., Liang, Gangning
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858672/
https://www.ncbi.nlm.nih.gov/pubmed/20421991
http://dx.doi.org/10.1371/journal.pgen.1000917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858672/
https://www.ncbi.nlm.nih.gov/pubmed/20421991
http://dx.doi.org/10.1371/journal.pgen.1000917

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