Two New Loci for Body-Weight Regulation Identified in a Joint Analysis of Genome-Wide Association Studies for Early-Onset Extreme Obesity in French and German Study Groups

Meta-analyses of population-based genome-wide association studies (GWAS) in adults have recently led to the detection of new genetic loci for obesity. Here we aimed to discover additional obesity loci in extremely obese children and adolescents. We also investigated if these results generalize by es...

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Autores principales: Scherag, André, Dina, Christian, Hinney, Anke, Vatin, Vincent, Scherag, Susann, Vogel, Carla I. G., Müller, Timo D., Grallert, Harald, Wichmann, H.-Erich, Balkau, Beverley, Heude, Barbara, Jarvelin, Marjo-Riitta, Hartikainen, Anna-Liisa, Levy-Marchal, Claire, Weill, Jacques, Delplanque, Jérôme, Körner, Antje, Kiess, Wieland, Kovacs, Peter, Rayner, Nigel W., Prokopenko, Inga, McCarthy, Mark I., Schäfer, Helmut, Jarick, Ivonne, Boeing, Heiner, Fisher, Eva, Reinehr, Thomas, Heinrich, Joachim, Rzehak, Peter, Berdel, Dietrich, Borte, Michael, Biebermann, Heike, Krude, Heiko, Rosskopf, Dieter, Rimmbach, Christian, Rief, Winfried, Fromme, Tobias, Klingenspor, Martin, Schürmann, Annette, Schulz, Nadja, Nöthen, Markus M., Mühleisen, Thomas W., Erbel, Raimund, Jöckel, Karl-Heinz, Moebus, Susanne, Boes, Tanja, Illig, Thomas, Froguel, Philippe, Hebebrand, Johannes, Meyre, David
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858696/
https://www.ncbi.nlm.nih.gov/pubmed/20421936
http://dx.doi.org/10.1371/journal.pgen.1000916

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