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Increased Asymmetric Dimethylarginine in Severe Falciparum Malaria: Association with Impaired Nitric Oxide Bioavailability and Fatal Outcome
Asymmetrical dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase (NOS), is a predictor of mortality in critical illness. Severe malaria (SM) is associated with decreased NO bioavailability, but the contribution of ADMA to the pathogenesis of impaired NO bioavailability and adve...
Autores principales: | Yeo, Tsin W., Lampah, Daniel A., Tjitra, Emiliana, Gitawati, Retno, Darcy, Christabelle J., Jones, Catherine, Kenangalem, Enny, McNeil, Yvette R., Granger, Donald L., Lopansri, Bert K., Weinberg, J. Brice, Price, Ric N., Duffull, Stephen B., Celermajer, David S., Anstey, Nicholas M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858698/ https://www.ncbi.nlm.nih.gov/pubmed/20421938 http://dx.doi.org/10.1371/journal.ppat.1000868 |
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