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Proteolysis of Human Thrombin Generates Novel Host Defense Peptides

The coagulation system is characterized by the sequential and highly localized activation of a series of serine proteases, culminating in the conversion of fibrinogen into fibrin, and formation of a fibrin clot. Here we show that C-terminal peptides of thrombin, a key enzyme in the coagulation casca...

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Detalles Bibliográficos
Autores principales:	Papareddy, Praveen, Rydengård, Victoria, Pasupuleti, Mukesh, Walse, Björn, Mörgelin, Matthias, Chalupka, Anna, Malmsten, Martin, Schmidtchen, Artur
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858699/ https://www.ncbi.nlm.nih.gov/pubmed/20421939 http://dx.doi.org/10.1371/journal.ppat.1000857

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