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Modulation of SOCS protein expression influences the interferon responsiveness of human melanoma cells

BACKGROUND: Endogenously produced interferons can regulate the growth of melanoma cells and are administered exogenously as therapeutic agents to patients with advanced cancer. We investigated the role of negative regulators of interferon signaling known as suppressors of cytokine signaling (SOCS) i...

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Detalles Bibliográficos
Autores principales: Lesinski, Gregory B, Zimmerer, Jason M, Kreiner, Melanie, Trefry, John, Bill, Matthew A, Young, Gregory S, Becknell, Brian, Carson, William E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858748/
https://www.ncbi.nlm.nih.gov/pubmed/20398276
http://dx.doi.org/10.1186/1471-2407-10-142