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Modulation of SOCS protein expression influences the interferon responsiveness of human melanoma cells
BACKGROUND: Endogenously produced interferons can regulate the growth of melanoma cells and are administered exogenously as therapeutic agents to patients with advanced cancer. We investigated the role of negative regulators of interferon signaling known as suppressors of cytokine signaling (SOCS) i...
Autores principales: | Lesinski, Gregory B, Zimmerer, Jason M, Kreiner, Melanie, Trefry, John, Bill, Matthew A, Young, Gregory S, Becknell, Brian, Carson, William E |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858748/ https://www.ncbi.nlm.nih.gov/pubmed/20398276 http://dx.doi.org/10.1186/1471-2407-10-142 |
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