Hematopoietic Stem Cell Transplantation after Posttransplant Lymphoproliferative Disorder

A 16-yr-old girl received liver transplantation for fulminant hepatitis. Aplastic anemia developed, and she received hematopoietic stem cell transplantation (HSCT). Eleven months after liver transplantation, abdominal lymph node enlargement and colon ulcers were observed, and colon biopsy showed pos...

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Detalles Bibliográficos
Autores principales: Kim, Min Joo, Kim, Inho, Bae, Hyun-Mi, Seo, Kyungsuk, Park, Namjun, Yoon, Sung-Soo, Park, Seonyang, Kim, Byoung Kook
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858841/
https://www.ncbi.nlm.nih.gov/pubmed/20436718
http://dx.doi.org/10.3346/jkms.2010.25.5.781
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author Kim, Min Joo
Kim, Inho
Bae, Hyun-Mi
Seo, Kyungsuk
Park, Namjun
Yoon, Sung-Soo
Park, Seonyang
Kim, Byoung Kook
author_facet Kim, Min Joo
Kim, Inho
Bae, Hyun-Mi
Seo, Kyungsuk
Park, Namjun
Yoon, Sung-Soo
Park, Seonyang
Kim, Byoung Kook
author_sort Kim, Min Joo
collection PubMed
description A 16-yr-old girl received liver transplantation for fulminant hepatitis. Aplastic anemia developed, and she received hematopoietic stem cell transplantation (HSCT). Eleven months after liver transplantation, abdominal lymph node enlargement and colon ulcers were observed, and colon biopsy showed posttransplant lymphoproliferative disorder (PTLD). Immunosuppression reduction was attempted, but it produced no therapeutic effect. Fourteen months after liver transplantation, she received a second HSCT due to engraftment failure, and PTLD resolved completely. The second HSCT can serve as cellular therapy for PTLD.
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spelling pubmed-28588412010-05-01 Hematopoietic Stem Cell Transplantation after Posttransplant Lymphoproliferative Disorder Kim, Min Joo Kim, Inho Bae, Hyun-Mi Seo, Kyungsuk Park, Namjun Yoon, Sung-Soo Park, Seonyang Kim, Byoung Kook J Korean Med Sci Case Report A 16-yr-old girl received liver transplantation for fulminant hepatitis. Aplastic anemia developed, and she received hematopoietic stem cell transplantation (HSCT). Eleven months after liver transplantation, abdominal lymph node enlargement and colon ulcers were observed, and colon biopsy showed posttransplant lymphoproliferative disorder (PTLD). Immunosuppression reduction was attempted, but it produced no therapeutic effect. Fourteen months after liver transplantation, she received a second HSCT due to engraftment failure, and PTLD resolved completely. The second HSCT can serve as cellular therapy for PTLD. The Korean Academy of Medical Sciences 2010-05 2010-04-16 /pmc/articles/PMC2858841/ /pubmed/20436718 http://dx.doi.org/10.3346/jkms.2010.25.5.781 Text en © 2010 The Korean Academy of Medical Sciences. http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kim, Min Joo
Kim, Inho
Bae, Hyun-Mi
Seo, Kyungsuk
Park, Namjun
Yoon, Sung-Soo
Park, Seonyang
Kim, Byoung Kook
Hematopoietic Stem Cell Transplantation after Posttransplant Lymphoproliferative Disorder
title Hematopoietic Stem Cell Transplantation after Posttransplant Lymphoproliferative Disorder
title_full Hematopoietic Stem Cell Transplantation after Posttransplant Lymphoproliferative Disorder
title_fullStr Hematopoietic Stem Cell Transplantation after Posttransplant Lymphoproliferative Disorder
title_full_unstemmed Hematopoietic Stem Cell Transplantation after Posttransplant Lymphoproliferative Disorder
title_short Hematopoietic Stem Cell Transplantation after Posttransplant Lymphoproliferative Disorder
title_sort hematopoietic stem cell transplantation after posttransplant lymphoproliferative disorder
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858841/
https://www.ncbi.nlm.nih.gov/pubmed/20436718
http://dx.doi.org/10.3346/jkms.2010.25.5.781
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