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A Teratocarcinoma-Like Human Embryonic Stem Cell (hESC) Line and Four hESC Lines Reveal Potentially Oncogenic Genomic Changes
The first Swiss human embryonic stem cell (hESC) line, CH-ES1, has shown features of a malignant cell line. It originated from the only single blastomere that survived cryopreservation of an embryo, and it more closely resembles teratocarcinoma lines than other hESC lines with respect to its abnorma...
Autores principales: | Hovatta, Outi, Jaconi, Marisa, Töhönen, Virpi, Béna, Frédérique, Gimelli, Stefania, Bosman, Alexis, Holm, Frida, Wyder, Stefan, Zdobnov, Evgeny M., Irion, Olivier, Andrews, Peter W., Antonarakis, Stylianos E., Zucchelli, Marco, Kere, Juha, Feki, Anis |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859053/ https://www.ncbi.nlm.nih.gov/pubmed/20428235 http://dx.doi.org/10.1371/journal.pone.0010263 |
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