SeSAW: balancing sequence and structural information in protein functional mapping

Motivation: Functional similarity between proteins is evident at both the sequence and structure levels. SeSAW is a web-based program for identifying functionally or evolutionarily conserved motifs in protein structures by locating sequence and structural similarities, and quantifying these at the l...

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Autores principales: Standley, Daron M., Yamashita, Reiko, Kinjo, Akira R., Toh, Hiroyuki, Nakamura, Haruki
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859130/
https://www.ncbi.nlm.nih.gov/pubmed/20299324
http://dx.doi.org/10.1093/bioinformatics/btq116
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author Standley, Daron M.
Yamashita, Reiko
Kinjo, Akira R.
Toh, Hiroyuki
Nakamura, Haruki
author_facet Standley, Daron M.
Yamashita, Reiko
Kinjo, Akira R.
Toh, Hiroyuki
Nakamura, Haruki
author_sort Standley, Daron M.
collection PubMed
description Motivation: Functional similarity between proteins is evident at both the sequence and structure levels. SeSAW is a web-based program for identifying functionally or evolutionarily conserved motifs in protein structures by locating sequence and structural similarities, and quantifying these at the level of individual residues. Results can be visualized in 2D, as annotated alignments, or in 3D, as structural superpositions. An example is given for both an experimentally determined query structure and a homology model. Availability and Implementation: The web server is located at http://www.pdbj.org/SeSAW/ Contact: standley@ifrec.osaka-u.ac.jp
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spelling pubmed-28591302010-04-26 SeSAW: balancing sequence and structural information in protein functional mapping Standley, Daron M. Yamashita, Reiko Kinjo, Akira R. Toh, Hiroyuki Nakamura, Haruki Bioinformatics Applications Note Motivation: Functional similarity between proteins is evident at both the sequence and structure levels. SeSAW is a web-based program for identifying functionally or evolutionarily conserved motifs in protein structures by locating sequence and structural similarities, and quantifying these at the level of individual residues. Results can be visualized in 2D, as annotated alignments, or in 3D, as structural superpositions. An example is given for both an experimentally determined query structure and a homology model. Availability and Implementation: The web server is located at http://www.pdbj.org/SeSAW/ Contact: standley@ifrec.osaka-u.ac.jp Oxford University Press 2010-05-01 2010-03-17 /pmc/articles/PMC2859130/ /pubmed/20299324 http://dx.doi.org/10.1093/bioinformatics/btq116 Text en © The Author(s) 2010. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/2.0/uk/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Applications Note
Standley, Daron M.
Yamashita, Reiko
Kinjo, Akira R.
Toh, Hiroyuki
Nakamura, Haruki
SeSAW: balancing sequence and structural information in protein functional mapping
title SeSAW: balancing sequence and structural information in protein functional mapping
title_full SeSAW: balancing sequence and structural information in protein functional mapping
title_fullStr SeSAW: balancing sequence and structural information in protein functional mapping
title_full_unstemmed SeSAW: balancing sequence and structural information in protein functional mapping
title_short SeSAW: balancing sequence and structural information in protein functional mapping
title_sort sesaw: balancing sequence and structural information in protein functional mapping
topic Applications Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859130/
https://www.ncbi.nlm.nih.gov/pubmed/20299324
http://dx.doi.org/10.1093/bioinformatics/btq116
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AT tohhiroyuki sesawbalancingsequenceandstructuralinformationinproteinfunctionalmapping
AT nakamuraharuki sesawbalancingsequenceandstructuralinformationinproteinfunctionalmapping

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