TopoGSA: network topological gene set analysis

Summary: TopoGSA (Topology-based Gene Set Analysis) is a web-application dedicated to the computation and visualization of network topological properties for gene and protein sets in molecular interaction networks. Different topological characteristics, such as the centrality of nodes in the network...

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Detalles Bibliográficos
Autores principales: Glaab, Enrico, Baudot, Anaïs, Krasnogor, Natalio, Valencia, Alfonso
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859135/
https://www.ncbi.nlm.nih.gov/pubmed/20335277
http://dx.doi.org/10.1093/bioinformatics/btq131
Descripción
Sumario:Summary: TopoGSA (Topology-based Gene Set Analysis) is a web-application dedicated to the computation and visualization of network topological properties for gene and protein sets in molecular interaction networks. Different topological characteristics, such as the centrality of nodes in the network or their tendency to form clusters, can be computed and compared with those of known cellular pathways and processes. Availability: Freely available at http://www.infobiotics.net/topogsa Contact: nxk@cs.nott.ac.uk; avalencia@cnio.es

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